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EPO — TIMP1
Text-mined interactions from Literome
Kadri et al., Cell Growth Differ 2000
(MAP Kinase Signaling System) :
Inhibition of the mitogen activated protein kinase pathway by the specific inhibitors PD98059 and U0126 and of phosphatidylinositol 3-kinase by LY294002, strongly inhibited
Epo induced
TIMP-1 expression and secretion
Kadri et al., Mol Cell Biol 2005
:
We report here that
erythropoietin regulates the transcription of the
TIMP-1 gene upon binding to its receptor in erythroid cells by triggering the activation of phosphatidylinositol 3-kinase (PI3K)/Akt