Gene interactions and pathways from curated databases and text-mining

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S100A2 — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Tan et al., FEBS Lett 1999 : Transcriptional activation of the human S100A2 promoter by wild-type p53 ... Transactivation assays using the promoter driven luciferase reporters revealed that the S100A2 promoter was transcriptionally activated by wild-type p53 , but not by p53 mutants, in a dose dependent as well as a p53 binding site dependent manner ... The p53 induced transactivation of the S100A2 promoter was enhanced by etoposide and blocked by a dominant negative p53 mutant
Shimamoto et al., J Biol Chem 2013 : Overexpression of S100A2 and S100P suppressed CHIP-chaperone complex dependent mutant p53 ubiquitination and degradation in Hep3B cells