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IFNG — RFX5

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: RFX5 → IFNG (increases) Xu et al., J Biol Chem 2003*
  Evidence: Protein levels of RFX5 increase in the nucleus during IFN-{gamma} treatment.
• OpenBEL Selventa BEL large corpus: RFX5 → IFNG (increases) Butticè et al., Circ Res 2006*
  Evidence: RFX5, a DNA-binding protein that recruits CIITA, is constitutively expressed and induced (3-fold) with time by IFNG in aortic SMCs (supplemental Figure II).

Text-mined interactions from Literome

Xu et al., J Biol Chem 2003 : Interferon gamma repression of collagen ( COL1A2 ) transcription is mediated by the RFX5 complex
Butticè et al., Circ Res 2006 (Atherosclerosis) : Moreover, simvastatin lowers the IFN-gamma induced expression of RFX5 and MHC II in addition to repressing collagen expression