Gene interactions and pathways from curated databases and text-mining

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FOS — TACR1

Text-mined interactions from Literome

Badie-Mahdavi et al., Eur J Neurosci 2001 (Second Messenger Systems) : These data support a causal relationship between protein kinase A- or C-dependent signal transduction, nociceptive afferent- or NK1R induced neuronal excitation and Fos expression in dorsal horn
Todd et al., J Neurosci 2002 : Formalin injection induced c-Fos in approximately 80 % of projection neurons with the NK1 receptor and in 25-45 % of those without it
Allen et al., Brain Res 2011 : These data demonstrate that in trigeminal subnucleus caudalis activation of either NK1 or NMDA receptors alone induces Fos expression ; protein kinases A and C are involved in NK1R induced Fos while protein kinase A is not required for NMDA receptor induced Fos
Chapman et al., J Neurophysiol 1996 (Edema...) : 6. Our results illustrate that NK1-receptor activation contributes to inflammatory evoked spinal c-Fos expression and thus supports the current contention that NK1-receptor activation, and by inference SP, plays a role in spinal nociceptive processing