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FOS — TACR1
Text-mined interactions from Literome
Badie-Mahdavi et al., Eur J Neurosci 2001
(Second Messenger Systems) :
These data support a causal relationship between protein kinase A- or C-dependent signal transduction, nociceptive afferent- or
NK1R induced neuronal excitation and
Fos expression in dorsal horn
Todd et al., J Neurosci 2002
:
Formalin injection
induced c-Fos in approximately 80 % of projection neurons with the
NK1 receptor and in 25-45 % of those without it
Allen et al., Brain Res 2011
:
These data demonstrate that in trigeminal subnucleus caudalis activation of either NK1 or NMDA receptors alone induces Fos expression ; protein kinases A and C are involved in
NK1R induced
Fos while protein kinase A is not required for NMDA receptor induced Fos
Chapman et al., J Neurophysiol 1996
(Edema...) :
6. Our results illustrate that
NK1-receptor activation
contributes to inflammatory evoked spinal
c-Fos expression and thus supports the current contention that NK1-receptor activation, and by inference SP, plays a role in spinal nociceptive processing