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IFNG — S100A4

Text-mined interactions from Literome

Takenaga et al., Br J Cancer 1999 (Adenocarcinoma...) : IFN-gamma also strongly suppressed the S100A4 mRNA expression in HT-29 cells, but weakly in Colo201 cells
Andersen et al., Br J Cancer 2003 (Breast Neoplasms...) : Interferon-gamma suppresses S100A4 transcription independently of apoptosis or cell cycle arrest ... Finally, microarray analysis suggests ISGF3G, ETV5, ZNF133 and CEBPG as possible candidate genes involved in IFN-gamma mediated repression of S100A4
Boye et al., Tumour Biol 2007 (Bone Neoplasms...) : Interferon-gamma induced suppression of S100A4 transcription is mediated by the class II transactivator ... We have previously shown that interferon-gamma (IFN-gamma) inhibits expression of the metastasis promoting protein S100A4 ... In the present study, we further explore the mechanism behind the IFN-gamma mediated effects on the human S100A4 promoter and demonstrate that IFN-gamma represses S100A4 promoter activity through induction of the class II transactivator (CIITA) ... The acidic domain in the N-terminal part of CIITA was crucial for the observed IFN-gamma induced inhibition of S100A4 promoter activity, probably by binding the histone acetyltransferase CBP/p300