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EPHB2 — HADHB

Text-mined interactions from Literome

Miggin et al., Mol Pharmacol 2002 : Although ERK activation through TPalpha was dependent on 2- [ 1- ( dimethylaminopropyl ) -1H-indol-3-yl ] -3- ( 1H-indol-3-yl ) -maleimide ( GF 109203X ) -sensitive protein kinase ( PK ) Cs, ERK activation through TPbeta was only partially dependent on PKCs. ERK activation through both TPalpha and TPbeta was dependent on PKA and phosphoinositide 3-kinase (PI3K) class 1 ( A ), but not class 1 ( B ), and was modulated by Harvey-Ras, A-Raf, c-Raf, and Rap1B/B-Raf and also involved transactivation of the epidermal growth factor receptor
Gallet et al., Biochem J 2003 : Moreover, we showed that both isoforms activate ERK phosphorylation in an Src-kinase dependent manner, whereas PKC was mainly implicated in ERK activation and EGFR phosphorylation by TP beta