Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
ATF4
→
EIF2AK3
(increases, EIF2AK3 Activity, ATF4 Activity)
Evidence: PERK mediates the transcriptional activation of the proteins LC3 and Atg5 in hypoxic responses through the action of the transcription factors ATF4 and CHOP, respectively (Rouschop et al., 2010).