Gene interactions and pathways from curated databases and text-mining

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ATF4 — EIF2AK3

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: ATF4 → EIF2AK3 (increases, EIF2AK3 Activity, ATF4 Activity)
    Evidence: PERK mediates the transcriptional activation of the proteins LC3 and Atg5 in hypoxic responses through the action of the transcription factors ATF4 and CHOP, respectively (Rouschop et al., 2010).