Gene interactions and pathways from curated databases and text-mining

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BAD — IL3

Text-mined interactions from Literome

Craddock et al., J Biol Chem 1999 : Expression of Deltap85 reduces IL-3 induced PKB phosphorylation and activation and phosphorylation of BAD dramatically, to levels seen in unstimulated cells
Korsmeyer et al., Cancer Res 1999 (Hyperplasia...) : In the presence of survival factor interleukin-3 , cells phosphorylate BAD on two serine residues
Yu et al., Mol Cell 2004 : IL-3 induces BAD phosphorylation at threonine 201, and replacement of threonine 201 by alanine generates a BAD mutant, which promotes IL-3 withdrawal induced apoptosis
del Peso et al., Science 1997 : Interleukin-3 induced phosphorylation of BAD through the protein kinase Akt ... BAD phosphorylation induced by interleukin-3 (IL-3) was inhibited by specific inhibitors of phosphoinositide 3-kinase ( PI 3-kinase )