Gene interactions and pathways from curated databases and text-mining

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IL3 — TCF23

Text-mined interactions from Literome

McDermott et al., Trends Mol Med 2002 (Familial Mediterranean Fever...) : Disorders of interleukin-1 processing and of regulation of nuclear factor kappaB transcription factor , and possibly defective apoptosis, might be involved in the pathogenesis of all but one of these disorders
Wang et al., Mol Cell Biol 2003 (MAP Kinase Signaling System) : Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen activated protein kinase dependent pathway
Yeung et al., Br J Haematol 2004 (Precursor Cell Lymphoblastic Leukemia-Lymphoma...) : The E4BP4 basic leucine zipper ( bZIP ) transcription factor is regulated by interleukin-3 (IL-3) in pro-B cells and has been reported to promote survival of the murine IL-3 dependent pro-B cell lines, FL5.12 and Baf-3
Sheikh et al., Hepatology 2008 (Hepatitis C...) : This transcription factor plays a key role in the expression of cytokines, tumor necrosis factor alpha (TNF-alpha), interleukin 6, interleukin 8, tumor growth factor beta, and Fas ligand
Chen et al., Immunity 2008 (Arthritis, Rheumatoid...) : IRF-4 binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor
Saraiva et al., Immunity 2009 : Interleukin-10 production by Th1 cells requires interleukin-12 induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose
Mui et al., EMBO J 1995 : In this paper, we describe the first molecular identification of a STAT transcription factor that is activated by IL-3
Sung et al., J Biol Chem 1993 : Stimulation of interleukin-1 gene transcription may be caused by the stimulation of transcription factor activities, including those of AP-1, by these protein phosphatase inhibitors
Barry et al., Blood 1997 : In contrast, a truncated IL-3R alpha with the N-terminal domain deleted interacts functionally with the beta chain ; mouse cells transfected with these receptor chains proliferate in response to human IL-3 and STAT5 transcription factor is activated