Gene interactions and pathways from curated databases and text-mining

◀ Back to IL12RB1

IL12RB1 — IL18

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Okazawa et al., Am J Gastroenterol 2002 (Crohn Disease...) : The functional activity of IL- 12 and IL-18 was assessed by the effect of recombinant IL-12 and recombinant IL-18 on interferon-gamma production, the proliferative response, and the induction of IL-2R, IL-12R , and IL-18R of LPLs
Frisancho-Kiss et al., Brain Res 2006 (Coxsackievirus Infections...) : We have previously reported that IL-12Rbeta1 signaling increases CVB3 induced myocarditis and IL-1beta/IL-18 levels in males, while IL-12 ( p35 ) /STAT4 induced IFN-gamma does not alter the severity of acute disease
Hyodo et al., J Immunol 1999 : These data suggested that NK cells develop and express IL-12R and IL-18R in the absence of IL-12 or IL-18, and that both IL-18 and IL-12 directly and independently augment perforin mediated cytotoxic activity of NK cells