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CPA1 — IL6

Text-mined interactions from Literome

Ramakers et al., Cytokine 2006 : In more detail, CPA potentiated TLR5 mediated IL-6 production, TLR3 mediated IFN-gamma production and TLR3 mediated Il-1beta production compared to TLR4 mediated stimulation
Marin et al., Toxicology 1996 : Without LPS stimulation, only IL-6 was increased by CPA at 5000 ng/ml after 1, 2 and 3 days ... IL-6 levels were increased in the presence of 100, 500 and 1000 CPA ng/ml at both 12 h and 3 days and in the presence of 100, 500, 1000 and 5000 ng/ml CPA at both 1 day and 2 days ... In the presence of LPS and CPA , however, IL-1 beta and IL-6 mRNA levels gradually increased up to 24 h reaching 2.5 and 29-fold higher than controls, respectively