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RAF1 — S100A12

Text-mined interactions from Literome

Yue et al., Eur J Pharmacol 2008 : Therefore, in the present study we examined the role of Raf-1 in sustained morphine mediated regulation of cAMP formation and basal CGRP release in vitro, in cultured neonatal rat dorsal root ganglion ( DRG ) neurons ... Since our present data also demonstrated that selective Raf-1 inhibitor, GW 5074, attenuated both the cAMP overshoot and the augmentation of CGRP release mediated by sustained morphine in neonatal rat DRG neurons, we suggest that Raf-1 mediated sensitization of the intracellular cAMP formation may play an important role in sustained morphine mediated augmentation of spinal pain neurotransmitter release
Tumati et al., Eur J Pharmacol 2008 (Hyperalgesia) : Recently we have demonstrated that inhibition of Raf-1 attenuates sustained morphine treatment mediated augmentation of CGRP release in vitro, in cultured primary sensory neurons