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ACE — EDN1

Text-mined interactions from Literome

Barton et al., J Cardiovasc Pharmacol 2000 (Body Weight) : Using the orally active endothelin-A- ( ET ( A ) ) receptor antagonist LU135252, we determined whether endothelin-1 (ET-1) and/or dietary fat may be involved in angiotensin converting enzyme (ACE) regulation in vivo
Kawaguchi et al., J Hypertens 1991 : We studied the effects of endothelin on angiotensin converting enzyme (ACE) in cultured pulmonary artery endothelial cells ... Calcium influx, phospholipase C and ACE activity were suppressed 60-70 % in the presence of endothelin-1 ( 10 ( -10 ) to 10 ( -6 ) mol/l ) by 50 microliters neomycin ... These results suggest that ACE was stimulated by endothelin-1 and that its activity may be closely related to phosphatidylinositol turnover stimulated by endothelin-1
Desideri et al., Mediators Inflamm 2008 : All the four tested ACE-I reduced endothelin-1 secretion and increased nitric oxide metabolite production by HUVECs ... The effect of ACE-I on endothelin-1 and nitric oxide metabolite production is mediated by the activation of bradykinin B ( 2 ) receptor being counteracted, at least in part, by a specific antagonist
Momose et al., Hypertension 1993 : These findings suggest that angiotensin I converting enzyme inhibitor inhibits endothelin-1 secretion by the accumulation of endogenous bradykinin in endothelial cells and that the inhibition of endothelin-1 secretion by bradykinin is mediated via B2 receptors
Moroi et al., Gen Pharmacol 1996 : We evaluated the effect of endothelin-1 (ET) on the angiotensin converting enzyme (ACE) activity in rat aortic smooth muscle cells ( VSMCs )
Brunner et al., Circulation 1996 (Arrhythmias, Cardiac...) : We tested the hypothesis that ACE inhibitor induced coronary protection and inhibition of reperfusion arrhythmias are mediated by suppression of cardiac endothelin-1 (ET-1) secretion and action
Teunissen et al., J Hypertens 1997 (Hypertension...) : Circulating endothelin levels did not differ significantly among patients with essential hypertension, hypertension with renal artery stenosis and proven renovascular hypertension and, although the renin-angiotensin system was clearly activated in members of the renovascular hypertension group, ACE inhibition did not affect their endothelin levels