◀ Back to EDN1

EDN1 — TGFB1

Text-mined interactions from Literome

Gandhi et al., Eur J Pharmacol 2000 (Liver Cirrhosis, Experimental) : Endothelin-1 stimulated TGF-beta1 and collagen synthesis via endothelin ET ( A ) and endothelin ET ( B ) receptors, respectively, in control stellate cells, but did not elicit these effects in the cirrhotic cells despite increased density of the respective receptor subtypes in them
Lee et al., Pulm Pharmacol Ther 2000 : Transforming growth factor-beta1 induces endothelin-1 in a bovine pulmonary artery endothelial cell line and rat lungs via cAMP
Stankevicius et al., Medicina (Kaunas) 2003 (Arteriosclerosis...) : The synthesis of endothelin-1 is induced by hypoxia, thrombin, interleukin-1, transforming growth factor-beta1 , vasopressin, and catecholamines
Rodríguez-Pascual et al., Circ Res 2003 : Functional cooperation between Smad proteins and activator protein-1 regulates transforming growth factor-beta mediated induction of endothelin-1 expression
Simonson et al., J Lab Clin Med 1992 : The fact that endothelin secretion is stimulated by cytokines, growth factors, and transforming growth factor beta is consistent with this role
Rodríguez-Pascual et al., J Cardiovasc Pharmacol 2004 : We have analyzed the mechanism by which transforming growth factor-beta increases endothelin-1 expression in vascular endothelial cells ... Transcriptional activation of the endothelin-1 promoter accounted for the transforming growth factor-beta induced increase in endothelin-1 mRNA levels ... Overexpression of the Smad3 isoform strongly potentiates transforming growth factor-beta- induced endothelin-1 promoter activity in a phosphorylation dependent manner ... These results demonstrate that transforming growth factor-beta induces endothelin-1 expression by a functional cooperation between Smads and activator protein-1 through activation of the Smad signaling pathway
Luo et al., Gastroenterology 2005 (Disease Models, Animal...) : We evaluated the sources of hepatic endothelin 1 production after common bile duct ligation in relation to thioacetamide cirrhosis and assessed whether transforming growth factor beta1 regulates endothelin 1 production ... Transforming growth factor beta1 also stimulated endothelin 1 promoter activity, expression, and production in normal rat cholangiocytes ... Transforming growth factor beta1 stimulates cholangiocyte endothelin 1 expression and production
Jain et al., Am J Respir Cell Mol Biol 2007 (Lung Injury...) : Endothelin-1 induces alveolar epithelial-mesenchymal transition through endothelin type A receptor mediated production of TGF-beta1 ... Endothelin-1 induces alveolar epithelial-mesenchymal transition through endothelin type A receptor mediated production of TGF-beta1
Rieder et al., Klin Wochenschr 1991 : In the presence of transforming growth factor beta a dose dependent increase of immunoreactive endothelin release was measured
Kurihara et al., Biochem Biophys Res Commun 1989 : An enzyme linked immunosorbent assay revealed that the levels of endothelin in endothelial cell conditioned media was also increased by TGF-beta 1 ... These results suggest that TGF-beta 1 , secreted by activated platelets, is involved not only in wound healing, but in the regulation of local vascular tone by stimulating endothelin production in the endothelial cells
Schnermann et al., Endocrinology 1996 : Regulation of endothelin production and secretion in cultured collecting duct cells by endogenous transforming growth factor-beta
Isumi et al., Endocrinology 1998 : Transforming growth factor beta1 and FCS suppressed AM secretion but stimulated endothelin-1 (ET-1) secretion