◀ Back to IRF6

CCR2 — IRF6

Text-mined interactions from Literome

Zhou et al., J Leukoc Biol 1999 (Listeriosis...) : We report here that lipopolysaccharides (LPS) down-regulated CCR2 expression both in vitro and in vivo
Xu et al., Eur J Immunol 2000 : We found that LPS induced a marked reduction in CCR2 cell surface protein levels which was blocked by pretreatment with the tyrosine kinase inhibitors genistein and herbimycin A
Lundien et al., J Clin Immunol 2002 : CCR2B was not merely present but also inducible by interleukin-2 (IL-2) and lipopolysaccharide (LPS)
Maus et al., Am J Respir Crit Care Med 2002 (Acute Disease...) : These findings confirm a central role for CCR2 in the process of alveolar monocyte recruitment in response to CCL2 alone and combined CCL2 plus LPS and reveal a previously unobserved interdependence between monocyte and neutrophil trafficking that has important implications for the concomitant increase in vascular permeability
Amat et al., Br J Pharmacol 2006 (Arthritis) : Surprisingly, CCR1 knockout mice produced more TNFalpha than controls in response to LPS , and J-113863 decreased TNFalpha also in CCR1 null mice, indicating that its effect was unrelated to CCR1
Jiang et al., J Immunol 2007 : NGF could markedly promote LPS induced expression of HLA-DR, CD40, CD80, CD83, CD86, CCR7 , secretion of IL-12p40 and proinflammatory cytokines IL-1, IL-6, TNF-alpha, and the T cell stimulating capacity of MoDCs, indicating that NGF can promote LPS induced DC maturation
Rosenson et al., Obesity (Silver Spring) 2009 (Metabolic Syndrome X) : In multivariate models including age, gender, and waist circumference, there were inverse correlations between changes in adiponectin and vascular cell adhesion molecule-1 ( VCAM-1 ) ( r = -0.54, P < 0.0001 ) and intercellular adhesion molecule-1 ( ICAM-1 ) ( r = -0.57, P < 0.0001 ), and C-reactive protein (CRP) ( r = -0.40, P = 0.0041 ) ; lipopolysaccharide (LPS) stimulated production of tumor necrosis factor-alpha (TNF-alpha) ( r = -0.30, P = 0.035 ), interleukin (IL)-1beta ( r = -0.44, P = 0.0016 ), monocyte chemotactic protein-1 (MCP-1) ( r = -0.46, P = 0.001 ), and macrophage inflammatory protein-1alpha ( MIP-1alpha ) ( r = -0.45, P = 0.0012 )
Gouwy et al., J Leukoc Biol 2009 : Furthermore, LPS rapidly induced the expression of IL-8/CXCL8 but not of the CCL2 receptor CCR2 in monocytic cells
Yang et al., Respir Physiol Neurobiol 2010 (Acute Lung Injury...) : Treatment with RS504393 had a noteworthy preventative effect on LPS induced over-expression of IL-1beta, plasminogen activator inhibitor and CCR2
van de Laar et al., J Immunol 2010 : Although dispensable for costimulatory molecule expression, the PI3K-PKB-mTOR signaling module was required for other important processes associated with DC function, including Ag uptake, LPS induced cytokine secretion, CCR7 expression, and T cell stimulation
Sica et al., J Exp Med 1997 : The present study was designed to investigate the effect of bacterial lipopolysaccharide (LPS) on C-C chemokine receptors ( CCR ) expressed in human mononuclear phagocytes ... LPS caused a rapid and drastic reduction of CCR2 mRNA levels, which binds MCP-1 and -3 ... As expected, LPS induced inhibition of CCR2 mRNA expression was associated with a reduction of both MCP-1 binding and chemotactic responsiveness
Xu et al., J Leukoc Biol 1997 : Furthermore, LPS stimulated the decay of Poly ( A ) CCR2 mRNA faster than total CCR2 RNA, indicating that deadenylation is the first step in LPS induced CCR2 RNA degradation
Minami et al., Toxicology 1998 : We investigated the penetration of cisplatin into the mouse cerebral cortex-rich region ( CCR ) induced by lipopolysaccharide (LPS) ... At doses of 500 mg/kg aminoguanidine, however, no effect was seen on the platinum level of the CCR induced by LPS