UCSC Genome Browser Gene Interaction Graph

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

Gene interactions and pathways from curated databases and text-mining

◀ Back to CASP8

CASP8 — CLTC

Pathways - manually collected, often from reviews:

NCI Pathway Database FAS (CD95) signaling pathway: FASLG/FAS (trimer)/FADD/FADD/CASP8/CASP8 complex (FAS-FASLG-FADD-CASP8) → clathrin heavy chain (CLTC) (translocation, collaborate)
Algeciras-Schimnich et al., Mol Cell Biol 2002, Algeciras-Schimnich et al., FEBS Lett 2003, Lee et al., EMBO J 2006, Lavrik et al., J Biol Chem 2008
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database FAS (CD95) signaling pathway: clathrin heavy chain (CLTC) → FADD/FADD/CASP8/CASP8 complex (FADD-CASP8) (translocation, activates)
Algeciras-Schimnich et al., Mol Cell Biol 2002, Algeciras-Schimnich et al., FEBS Lett 2003, Lee et al., EMBO J 2006, Lavrik et al., J Biol Chem 2008
Evidence: mutant phenotype, assay, physical interaction