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TP53 — TSC1
Text-mined interactions from Literome
Feng et al., Cancer Res 2007
(Cell Transformation, Neoplastic) :
The
regulation of AMPK beta1,
TSC2 , and PTEN expression by
p53 : stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways
Lee et al., EMBO J 2007
(Hamartoma...) :
Thus, loss of
TSC1 or TSC2, the negative regulators of mTOR,
results in dramatic accumulation of
p53 and apoptosis in response to stress conditions
Yoon et al., PloS one 2012
(Uterine Cervical Neoplasms) :
Interestingly,
TSC-22 did not
affect the interaction between
p53 and HDM2