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BCR — MAP3K1
Text-mined interactions from Literome
Nawata et al., Oncogene 2003
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
These results indicate that
MEKK1 is a downstream target of Bcr-Abl, and that the antiapoptotic effect of
Bcr-Abl in chronic myelogenous leukemia cells is
mediated via the MEKK1-NF-kappaB pathway
Nakamura et al., Oncogene 2005
(Cell Transformation, Neoplastic...) :
Bcr-Abl enhanced
MEKK1 expression in ES transfectants, as it does in other Bcr-Abl transformed cells