Gene interactions and pathways from curated databases and text-mining

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HDAC3 — IRF6

Text-mined interactions from Literome

Aung et al., FASEB J 2006 (Inflammation) : LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression
Jennewein et al., J Immunol 2008 : Chromatin immunoprecipitation analysis demonstrated that AC prevented the LPS induced removal of nuclear receptor corepressor (NCoR) from the kappaB site within the TNF-alpha promoter
Zhang et al., J Cardiovasc Pharmacol 2012 (Disease Models, Animal...) : Moreover, blockade of GC-GR signaling pathway by adrenalectomy, RU486 or TSA enhanced LPS induced myocardial nuclear factor-?B activation and histone acetylation but inhibited myocardial histone deacetylase expression and activity
Finlin et al., Metab Syndr Relat Disord 2012 : Small interfering RNA ( siRNA ) -mediated knockdown of SUMO-1 decreased PPAR?, HDAC3, and NCoR in THP-1 cells and increased tumor necrosis factor-a (TNF-a) induction in response to lipopolysaccharide (LPS) ... Small interfering RNA ( siRNA ) -mediated knockdown of SUMO-1 decreased PPAR?, HDAC3 , and NCoR in THP-1 cells and increased tumor necrosis factor-a (TNF-a) induction in response to lipopolysaccharide (LPS)