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KCNMA1 — PRKAR2B
Text-mined interactions from Literome
Tian et al., Proc Natl Acad Sci U S A 2008
:
Thus, palmitoylation gates
BK channel regulation by
PKA phosphorylation
Perry et al., Am J Physiol Gastrointest Liver Physiol 2009
(Ion Channel Gating) :
Since many channel proteins are regulated by phosphorylation, we evaluated the
roles of
protein kinase A (PKA) and phosphatases in the modulation of apical
BK channel activity in surface colonocytes from rat distal colon using patch-clamp techniques, having first increased channel abundance by chronic dietary K+ enrichment
Liu et al., American journal of physiology. Renal physiology 2009
(Mechanotransduction, Cellular) :
Interpretation of these results in light of the effects of these inhibitors on the flow induced elevation of [ Ca2+ ] ( i ) suggests that the principal cell apical
BK channel is tonically
inhibited by
PKA and that flow stimulation of J ( K ) in the CCD is PKA and PKC dependent
Zhou et al., Proc Natl Acad Sci U S A 2010
:
PKC phosphorylation at S ( 1151 ) also influences
stimulation of
BK channel activity by protein kinase G ( PKG ) and
protein kinase A (PKA)
Tian et al., J Biol Chem 1998
:
However,
PKA mediated inhibition of
BK channel activity in isolated patches from steroid treated cells was severely blunted