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AKT1 — SP1

Text-mined interactions from Literome

Bae et al., Cancer Res 2006 (Adenocarcinoma...) : The inhibition of PI3K/Akt signaling also prevented Sp1 activation
Jin et al., Cell Signal 2007 : Also, suppression of Akt activation blocked the expression of Redd1 and the activation of HIF-1alpha and Sp1 by CoCl ( 2 ) and HCD
Qureshi et al., Cell Signal 2007 : Phosphatidylinositol kinase ( PI3K ) inhibitors, Wortmannin and LY294002 and Akt inhibitor ( NL-71-101 ) significantly inhibited TGF-beta induced Akt phosphorylation, TIMP-3 expression, TIMP-3 promoter ( -940 to +376 ) -driven luciferase activity and Sp1 transcription factor binding
Pang et al., International journal of molecular sciences 2013 : Furthermore, resistin enhanced DNA binding activity of Sp1 with VEGF promoter in a PI3K/Akt dependent manner ... PI3K/Akt activated by resistin led to increasing interaction with Sp1 , triggering a progressive phosphorylation of Sp1 on Thr453 and Thr739, resulting in the upregulation of VEGF expression