Gene interactions and pathways from curated databases and text-mining
IRF6: top 25 interacting genes (chr1:209958967-209979520)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IRF6-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IRF6, not among the Top 25
Other genes interacting with IRF6. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

MAPK7 ▸ MAPK6 ▸ IFNG ▸ EPHB2 ▸ NFKBIA ▸ NOS1 ▸ CCL2 ▸
CD14 ▸ ICAM1 ▸ CPOX ▸ IL4 ▸ JUN ▸ IL18 ▸ IL2 ▸
NOS3 ▸ IL5 ▸ IL13 ▸ FOS ▸ PTBP1 ▸ PTBP2 ▸ HNRNPH1 ▸
HNRNPF ▸ IL3 ▸ IL15 ▸ IL33 ▸ IL19 ▸ IL21 ▸ IL37 ▸
IL32 ▸ IL16 ▸ IL31 ▸ IL11 ▸ IL9 ▸ IL24 ▸ IL7 ▸
IL20 ▸ IL22 ▸ IL34 ▸ IL25 ▸ IL26 ▸ IL27 ▸ TLR2 ▸
CSF2 ▸ MMP9 ▸ AKT1 ▸ AKT2 ▸ SYT1 ▸ AHSA1 ▸ AKT3 ▸
CASP1 ▸ CASP3 ▸ CXCL10 ▸ CASP4 ▸ CASP9 ▸ CASP8 ▸ CASP6 ▸
CASP16 ▸ CASP7 ▸ CASP5 ▸ CASP2 ▸ CASP12 ▸ CASP14 ▸ CASP10 ▸
IFNB1 ▸ VCAM1 ▸ IL1RN ▸ RNF19A ▸ GRAP2 ▸ UMOD ▸ WNK1 ▸
LBP ▸ SELE ▸ TLR3 ▸ TLR9 ▸ HMOX1 ▸ TLR1 ▸ CCL3 ▸
ANXA6 ▸ TLR7 ▸ CFP ▸ VEGFA ▸ TLR5 ▸ CRK ▸ LANCL1 ▸
TLR6 ▸ TLR8 ▸ GPI ▸ TLR10 ▸ MMP2 ▸ CD86 ▸ STAT1 ▸
CD79A ▸ CD40 ▸ HMGB1 ▸ MMP1 ▸ MPO ▸ NOX1 ▸ CHUK ▸
ITGAM ▸ IKBKB ▸ POLDIP2 ▸ CD80 ▸ STAT3 ▸ IRF3 ▸ NOX4 ▸
MMP3 ▸ MIP ▸ MYD88 ▸ TP63 ▸ MMP13 ▸ MUC1 ▸ NOX3 ▸
NOX5 ▸ MUC2 ▸ CA2 ▸ MMP8 ▸ MMP14 ▸ TGFB1 ▸ IRAK1 ▸
MUC7 ▸ MMP12 ▸ CXCL1 ▸ MMP11 ▸ MMP20 ▸ MMP27 ▸ MMP19 ▸
MMP28 ▸ MUC16 ▸ RABEPK ▸ MUC4 ▸ MMP7 ▸ MMP15 ▸ MMP25 ▸
CXCL2 ▸ MMP16 ▸ MMP24 ▸ CD46 ▸ MMP17 ▸ MMP26 ▸ MMP10 ▸
MMP21 ▸ TCF25 ▸ TCF19 ▸ MUC22 ▸ MUC20 ▸ TCF21 ▸ TCF3 ▸
MUC13 ▸ TCF4 ▸ MUC19 ▸ TCF20 ▸ TCF24 ▸ MUC21 ▸ MUC17 ▸
TCF23 ▸ MUC8 ▸ MUC15 ▸ MUC6 ▸ IKBKG ▸ TCF7 ▸ TCF12 ▸
MUC12 ▸ CXCL9 ▸ TCF15 ▸ HLA-DRA ▸ PAF1 ▸ CTR9 ▸ WDR61 ▸
CXCL12 ▸ SERPINE1 ▸ LEO1 ▸ CXCL11 ▸ LYZ ▸ CDC73 ▸ IRF1 ▸
CXCL5 ▸ PTGS1 ▸ CXCL13 ▸ LEP ▸ HLA-DRB1 ▸ PLA2G4A ▸ CXCL16 ▸
SOD1 ▸ ITGB2 ▸ IRAK4 ▸ MIPEP ▸ C1orf228 ▸ CXCL6 ▸ SOD3 ▸
SOD2 ▸ CSF3 ▸ PI3 ▸ PGF ▸ CXCL14 ▸ IL23A ▸ CXCL17 ▸
IDO1 ▸ CXCL3 ▸ HDC ▸ REL ▸ CRH ▸ PIK3R1 ▸ PIK3CA ▸
HGF ▸ PDCD11 ▸ EGR1 ▸ LTB ▸ IRAK3 ▸ CD83 ▸ CSF1 ▸
SOCS3 ▸ SAA1 ▸ MYLIP ▸ PLA2G1B ▸ SLC25A10 ▸ ICAM5 ▸ ICAM4 ▸
ICAM3 ▸ ICAM2 ▸ NANOS2 ▸ NM ▸ IRAK2 ▸ MUC5AC ▸ INS ▸
NUP43 ▸ FAS ▸ ARG1 ▸ CCR2 ▸ EDN1 ▸ BPI ▸ CD4 ▸
TNFSF11 ▸ TBCE ▸ PTGES ▸ MIF ▸ TNPO1 ▸ CEBPB ▸ SLPI ▸
IGF1 ▸ SOAT1 ▸ SETD2 ▸ DUSP1 ▸ CCL4 ▸ HDAC1 ▸ FASLG ▸
CREB5 ▸ CAT ▸ IRF7 ▸ CREB3 ▸ DEFB4B ▸ CEBPA ▸ NCF1 ▸
CREB1 ▸ MAP3K8 ▸ IFI44 ▸ SRC ▸ ARF6 ▸ CRP ▸ IRF2 ▸
CD69 ▸ ARF4 ▸ MDM1 ▸ ARF5 ▸ MDM2 ▸ MDM4 ▸ S100A12 ▸
ARF3 ▸ HDAC2 ▸ ARF1 ▸ SELP ▸ PTX3 ▸ CCL20 ▸ ARG2 ▸
GP9 ▸ GP2 ▸ PLD6 ▸ PLD2 ▸ APOE ▸ GP5 ▸ RHOA ▸
NGF ▸ PLD3 ▸ CCR7 ▸ MTOR ▸ PLD5 ▸ NFKBIB ▸ PLD4 ▸
IRF4 ▸ PPARG ▸ IRF8 ▸ TNFRSF11B ▸ PLD1 ▸ RAC1 ▸ SLC17A5 ▸
ABCC1 ▸ PLG ▸ RBBP4 ▸ CISH ▸ HIF1A ▸ GP6 ▸ PGD ▸
CCR5 ▸ TRAF6 ▸ CCL5 ▸ ALB ▸ AVP ▸ BAX ▸ CDCA5 ▸
SERPINB2 ▸ PRKCA ▸ AGTR2 ▸ CD40LG ▸ APOB ▸ NOD2 ▸ TIMP1 ▸
APC ▸ CORT ▸ AHR ▸ GJA1 ▸ BDNF ▸ JAK2 ▸ BCL2 ▸
ZFP36 ▸ SP1 ▸ TREM1 ▸ GIT2 ▸ PPARA ▸ MAPKAPK2 ▸ ADAM11 ▸
HBD ▸ IL17D ▸ CCND1 ▸ FCER2 ▸ CXCR4 ▸ LY96 ▸ IL1R1 ▸
LTF ▸ ODC1 ▸ IL2RA ▸ STS ▸ HSPG2 ▸ RBBP7 ▸ EGFR ▸
PDE4B ▸ LCN2 ▸ GNRH1 ▸ F3 ▸ IRF5 ▸ IFNA4 ▸ ATP5O ▸
TBK1 ▸ LYN ▸ CALM3 ▸ IRF9 ▸ LITAF ▸ BCL10 ▸ CAV1 ▸
ATF2 ▸ LPL ▸ SELL ▸ PLAU ▸ LIF ▸ IFNA2 ▸ EIF2AK2 ▸
SAP130 ▸ MT3 ▸ NA ▸ TFPI ▸ SUDS3 ▸ SAP30 ▸ RAF1 ▸
PARP1 ▸ GDNF ▸ ADM ▸ PRDX2 ▸ SLC27A5 ▸ PTK7 ▸ PTK2 ▸
MNAT1 ▸ BCL3 ▸ BTK ▸ CCR6 ▸ AGTR1 ▸ HSPD1 ▸ SOCS1 ▸
MLYCD ▸ NCF2 ▸ CCR3 ▸ PRL ▸ CYP3A ▸ CSRP1 ▸ TNFSF10 ▸
ATP8A2 ▸ MOCOS ▸ P2RX7 ▸ IL17A ▸ SPP1 ▸ PTK6 ▸ SIN3A ▸
GAL ▸ UCN ▸ TNFSF13B ▸ CD2 ▸ ARID4B ▸ IKBKAP ▸ ACE ▸
ACP2 ▸ CEBPD ▸ ECM2 ▸ PRG3 ▸ MAP3K14 ▸ CD276 ▸ IFNA17 ▸
IFNA21 ▸ IFNA14 ▸ IFNA10 ▸ MAP2K1 ▸ CCR9 ▸ NOTCH1 ▸ NLRP3 ▸
ECM1 ▸ CXCR1 ▸ MOK ▸ CCR10 ▸ TGFB2 ▸ IFNA7 ▸ RELB ▸
CSE ▸ IFNA1 ▸ STAT5A ▸ CCR1 ▸ GCHFR ▸ APP ▸ TP53 ▸
IFNA16 ▸ LIPA ▸ IFNA13 ▸ MSH3 ▸ ETS2 ▸ IFNA8 ▸ CD8A ▸
IFNA6 ▸ CCR8 ▸ CD44 ▸ CCR4 ▸ ADAM17 ▸ PHKA2 ▸ PRG2 ▸
JAK1 ▸ CRAT ▸ NEDD9 ▸ PRG4 ▸ SLC22A3 ▸ RETN ▸ IFNA5 ▸
CEL ▸ SETBP1 ▸ SPHK1 ▸ IL2RB ▸ LDLR ▸ FGB ▸ MSH2 ▸
OCLN ▸ NOTCH4 ▸ TF ▸ EIF4EBP1 ▸ SYK ▸ OLR1 ▸ MSH6 ▸
CNR2 ▸ BCL9 ▸ PAM ▸ SERPING1 ▸ HDAC11 ▸ TGFB3 ▸ BCL5 ▸
CCL24 ▸ ANXA1 ▸ NEU1 ▸ MSH4 ▸ EDN2 ▸ S100A8 ▸ PLIN2 ▸
UCP2 ▸ NOTCH3 ▸ PTPN11 ▸ THBD ▸ SLCO6A1 ▸ BCL6 ▸ SH3D19 ▸
TXN ▸ TNFRSF1A ▸ TNP2 ▸ TNP1 ▸ SAA2 ▸ TRAM2 ▸ WAS ▸
CRYGEP ▸ MAF ▸ ABCA1 ▸ CD55 ▸ CAMP ▸ NOTCH2 ▸ GIF ▸
ABCB1 ▸ F2RL1 ▸ LTA ▸ GHR ▸ ATF3 ▸ TNFRSF1B ▸ CAV3 ▸
FBXO32 ▸ SAA4 ▸ F2R ▸ CXCR2 ▸ TRAM1 ▸ IGFBP3 ▸ MSH5 ▸
TYK2 ▸ CADM1 ▸ RAC2 ▸ PLAUR ▸ APCS ▸ EDN3 ▸ PCBD1 ▸
NOD1 ▸ ALG1 ▸ HDAC3 ▸ C9orf3 ▸ SIGLEC7 ▸ PRKAA2 ▸ CD28 ▸
PRKAB1 ▸ NPY4R ▸ SIGIRR ▸ ACHE ▸ UBL3 ▸ FXR1 ▸ JUNB ▸
GPX4 ▸ GPX5 ▸ STX1A ▸ PRKAG1 ▸ CCND2 ▸ COA4 ▸ ANXA5 ▸
ALPI ▸ COA1 ▸ MARCKS ▸ CX3CL1 ▸ TSPO ▸ ADCY9 ▸ CDH13 ▸
MAP3K7 ▸ COA3 ▸ SMC6 ▸ HDAC6 ▸ FPR1 ▸ S7 ▸ VIP ▸
BIRC3 ▸ GFAP ▸ CETP ▸ GPX6 ▸ JUND ▸ POMC ▸ MT4 ▸
TOLLIP ▸ DDIT3 ▸ NPPA ▸ CEBPZ ▸ NEU4 ▸ PRKAA1 ▸ PLCG1 ▸
EIF4E ▸ LPO ▸ CIITA ▸ PPARGC1A ▸ GAST ▸ ICOSLG ▸ ISG15 ▸
TECR ▸ VIPR1 ▸ GPX7 ▸ GSK3B ▸ COA5 ▸ ACO1 ▸ GPX3 ▸
FXR2 ▸ CYP2B6 ▸ AGXT ▸ SEC14L2 ▸ CD38 ▸ CD1A ▸ CTRL ▸
GATA2 ▸ POU2F2 ▸ TFRC ▸ ELAVL1 ▸ HP ▸ CD19 ▸ CHD4 ▸
DDX58 ▸ UPK3B ▸ ARC ▸ CNP ▸ PTX4 ▸ HMGCR ▸ CTSB ▸
SCARB1 ▸ SLC7A2 ▸ FADD ▸ PRKAG2 ▸ GPX8 ▸ GPX2 ▸ LOX ▸
GPX1 ▸ A2M ▸ AQP5 ▸ SLC2A1 ▸ TRAF1 ▸ RPTOR ▸ IFIT2 ▸
PRDX1 ▸ PGC ▸ MTA2 ▸ SMC5 ▸ FGFR3 ▸ PRKAB2 ▸ SMC2 ▸
CD8B ▸ GATA3 ▸ NAALADL1 ▸ WNT2 ▸ SMC4 ▸ MRXS5 ▸ PGP ▸
TYR ▸ ITGAX ▸ EPB42 ▸ CES1 ▸ CTLA4 ▸ GIT1 ▸ JAK3 ▸
PLTP ▸ OXTR ▸ CDC42 ▸ NEU2 ▸ NEU3 ▸ S12 ▸ CAV2 ▸
CCL18 ▸ S11 ▸ PLAT ▸ SMC3 ▸ MET ▸ COA6 ▸ CYBB ▸
AQP1 ▸ G6PD ▸ PGR ▸ ABL1 ▸ CD1D ▸ FGF9 ▸ RPS6KB1 ▸
SMAD7 ▸ SLC9A1 ▸ CD58 ▸ PARP2 ▸ USP7 ▸ ERP44 ▸ CYP4F22 ▸
ADCY4 ▸ PPP2CA ▸ CX3CR1 ▸ CES3 ▸ LAMP2 ▸ TXNRD2 ▸ CYP4F12 ▸
SPHK2 ▸ ACSL1 ▸ CADM4 ▸ FCGR1A ▸ AQP8 ▸ NANOS1 ▸ S100A9 ▸
GPS2 ▸ NCF4 ▸ FMR1 ▸ MTA1 ▸ CYP4F3 ▸ P2RX4 ▸ PKD3 ▸
CAPN14 ▸ CAPN2 ▸ MICE ▸ CAPN3 ▸ NR1I2 ▸ CAPN13 ▸ MAP2K6 ▸
TPGS1 ▸ IL13RA1 ▸ KHSRP ▸ VWF ▸ ITGAL ▸ SERPINB6 ▸ HDAC10 ▸
PKD1 ▸ CYP4F8 ▸ ADCY7 ▸ MCM6 ▸ RHOB ▸ REG3A ▸ LGALS3 ▸
PRDX5 ▸ ELANE ▸ QRICH2 ▸ TNFSF13 ▸ IL1R2 ▸ IDS ▸ MCM3 ▸
MCM4 ▸ PKD2 ▸ PARP14 ▸ HDAC9 ▸ LAMP3 ▸ BDKRB1 ▸ NTRK1 ▸
RNPEP ▸ SP100 ▸ INSR ▸ PARP11 ▸ CAPN12 ▸ PLCG2 ▸ PRTN3 ▸
CD5 ▸ MBD3 ▸ KLK3 ▸ MCM7 ▸ STAR ▸ MST1R ▸ SMAD4 ▸
MTDH ▸ ADCY6 ▸ LAMP5 ▸ PLEK ▸ QRICH1 ▸ SLC5A1 ▸ PARP15 ▸
CCL4L2 ▸ CAPN15 ▸ MAP2K3 ▸ NPY ▸ GATA5 ▸ PARP9 ▸ CAPN9 ▸
ADCY1 ▸ MCM5 ▸ PECAM1 ▸ PRX ▸ ERF ▸ RSAD2 ▸ PRKAR2B ▸
HDAC8 ▸ NQO1 ▸ EPS15 ▸ CYP4F11 ▸ CYP4F2 ▸ CPP ▸ NTF3 ▸
IFN1@ ▸ MCS ▸ CAPN10 ▸ ADCY8 ▸ IL18BP ▸ AKT1S1 ▸ PARP4 ▸
TIMP3 ▸ SMN1 ▸ PARP3 ▸ CORO2A ▸ MARCO ▸ ACAN ▸ GSR ▸
PLN ▸ RHO ▸ AMBP ▸ USP14 ▸ HDAC7 ▸ HDAC5 ▸ IL6R ▸
TPO ▸ PVR ▸ CPZ ▸ AQP4 ▸ TPX2 ▸ AQP2 ▸ PDGFA ▸
TAT ▸ ITGB1 ▸ MCM2 ▸ KCNMA1 ▸ AGT ▸ NPR1 ▸ CAPN6 ▸
FOXP3 ▸ DST ▸ PRDM1 ▸ IL1RAP ▸ NCOR1 ▸ GATA6 ▸ ASS1 ▸
CAPN5 ▸ CLU ▸ TUBGCP2 ▸ PRKAR2A ▸ PPP2R1A ▸ BCR ▸ KCNH4 ▸
PARP6 ▸ GATA1 ▸ IL2RG ▸ RIPK2 ▸ MAP2K2 ▸ PTHLH ▸ C5AR1 ▸
ERP27 ▸ RASIP1 ▸ ERP29 ▸ CADM3 ▸ MUC5B ▸ NFKBIZ ▸ GLA ▸
CNR1 ▸ EPS8 ▸ IGH ▸ PPP2R2B ▸ KITLG ▸ NDUFAB1 ▸ PARP12 ▸
CES2 ▸ VDR ▸ CAPN7 ▸ KLF4 ▸ PDCD1LG2 ▸ ADCY10 ▸ CCL1 ▸
PIR ▸ HCLS1 ▸ C1QB ▸ ETS1 ▸ CD9 ▸ C1QA ▸ MT-CYB ▸
CAPN8 ▸ GALT ▸ IRG1 ▸ PRKACB ▸ ADCY2 ▸ HDAC4 ▸ PARP8 ▸
BCAP31 ▸ MEPE ▸ SDC2 ▸ OSM ▸ PTEN ▸ LGALS1 ▸ MCOLN1 ▸
TFAP2A ▸ EPB41 ▸ ISG20 ▸ PRKAR1A ▸ ADCY5 ▸ TPGS2 ▸ GATA4 ▸
IKBKE ▸ PDCD2 ▸ WNT5A ▸ FGF2 ▸ PRKAR1B ▸ CTSL ▸ MAL ▸
PRKCB ▸ FEV ▸ SIRT1 ▸ NR4A1 ▸ S1PR1 ▸ PLA2G7 ▸ PDGFB ▸
LAMP1 ▸ SLC11A2 ▸ TBL1X ▸ C4BPA ▸ DOK3 ▸ SREBF1 ▸ CAPN1 ▸
S1PR3 ▸ CLDN1 ▸ SST ▸ MLST8 ▸ ADCY3 ▸ ESAM ▸ HSP90AA1 ▸
FST ▸ LTC4S ▸ F12 ▸ TRIM63 ▸ CAPN11 ▸ CADM2 ▸ PMPCB ▸
CTNNB1 ▸ PRKACG ▸ LRP1 ▸ HAMP ▸ TBL1XR1 ▸ EDNRA ▸ FPR2 ▸
PPARD ▸ SDC4 ▸ APOA1 ▸ PARP10 ▸ PARP16 ▸ SPAG8 ▸ ADAMTS5 ▸
CYP1A2 ▸ CROT ▸ FGF21 ▸ HPGDS ▸ FOSL1 ▸ CYP1A1 ▸ PCAF ▸
TAF1 ▸ ONECUT1 ▸ MID1 ▸ CREBBP ▸ TLX2 ▸ SMARCD1 ▸ COPS5 ▸
GTF2E1 ▸ BNC2 ▸ NR3C1 ▸ GTF3A ▸ COPS6 ▸ UBC ▸ COPS4 ▸
CDK4 ▸ ZBTB3 ▸ COPS2 ▸ ARHGAP29 ▸ GTF2A1 ▸ RFX3 ▸ GPS1 ▸
Data information
Please see the Gene Interactions Track Manual.