◀ Back to IRF6
CAT — IRF6
Text-mined interactions from Literome
Kim et al., Mol Cells 1999
:
CAT activity was not
induced by
LPS in constructs containing only the octamer motif ( -71 to +82 ), but was induced with constructs containing the octamer motif and the upstream sequences of the NF-kappaB site ( -91 to +82 )
Lee et al., Toxicol Lett 2000
:
AAF treatment of 70Z/3 cells resulted in a significant inhibition of
CAT activity
induced by
LPS
Pawate et al., J Neurosci Res 2004
(Encephalitis...) :
Phox inhibitors and
catalase also suppressed LPS/IFNgamma induced expression of cytokines, i.e., interleukin (IL)-1, IL-6, and tumor necrosis factor (TNF)alpha and
blocked LPS activation of MAP kinases ( i.e., p38 MAPK, c-Jun N-terminal kinase and extracellular signal regulated kinase ), NFkappaB, and IFNgamma induced STAT1 phosphorylation
Huang et al., Acta Anaesthesiol Scand 2004
:
Attenuation of
LPS induced iNOS,
CAT-2 , and CAT-2B induction significantly inhibited NO biosynthesis and lessened lung injury
Lao et al., Acta Anaesthesiol Taiwan 2006
:
In addition, the pre-treatment of ST36 acupuncture significantly attenuated the
LPS induced expressions of iNOS,
CAT-2 , CAT-2B, and GTPCH in stimulated rat lungs ... Pre-treatment of acupuncture stimulation of ST36 had significantly inhibitory effects on
LPS induced iNOS,
CAT-2 , CAT-2B, and GTPCH expressions in septic rat lungs
Fan et al., Shock 2007
(Shock, Hemorrhagic) :
The antioxidant polyethylene glycol
catalase markedly decreased MyD88 dependent activation of IL-1 receptor associated kinase 4 and TLR2 expression in the AM in
response to
LPS
Radolf et al., J Immunol 1991
:
Several lines of evidence indicated that the induction of TNF and CAT was attributable to the spirochete lipoproteins rather than to contaminating or endogenous LPS : 1 ) the dose response curves observed for the lipoproteins were markedly different from those obtained with LPS ; 2 ) lipoprotein mediated activation was unaffected by amounts of polymyxin B that completely neutralized the
induction of TNF and
CAT by
LPS , 3 ) low concentrations of the lipoproteins induced TNF in macrophages from endotoxin-unresponsive C3H/HeJ mice as effectively as in macrophages from normal C3H/HeN mice, and 4 ) isolated spirochete lipoproteins, but not a non-lipoprotein immunogen, were potent inducers of CAT in the transformed macrophages
Sebai et al., Drug Chem Toxicol 2011
(Disease Models, Animal...) :
We found that resveratrol counteracted LPS induced lipoperoxidation and decreased superoxide dismutase ( SOD ) activity, but had no effect on the
LPS induced decrease in
catalase (CAT) nor on the increase in peroxidase ( POD ) activity
Phan et al., Lab Invest 1984
(Pulmonary Fibrosis) :
LPS alone
had no significant effect on total lung
catalase activity
Dierks et al., Mol Immunol 1994
:
Stimulation with IL-4 plus
LPS resulted in only a modest increase in
CAT activity ( approximately 2-fold ), in contrast to transcription assays, where increases approximated that seen at the cell surface
Deng et al., J Immunol 1994
:
In contrast,
LPS induced
CAT expression was unaffected under identical experimental conditions
Ohmori et al., J Biol Chem 1993
:
The ability of
LPS to
stimulate CAT via the ISRE was apparently mediated by intermediate expression of endogenous IFN alpha/beta