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NUP43 — UCN

Text-mined interactions from Literome

Brar et al., J Biol Chem 2000 (MAP Kinase Signaling System...) : UCN caused rapid phosphorylation of ERK1/2-p42/44 , and PD98059, which blocks the MEK1-ERK1/2-p42/44 cascade, also inhibited the survival promoting effect of UCN
Brar et al., Endocrinology 2004 : Using Chinese hamster ovary cells stably expressing CRFR1 and CRFR2beta, we show that Ucn-I , Ucn-II and Ucn-III activate ERK1/2-p42 , 44 via CRFR2beta ... CRF and Ucn-I but not Ucn-II or Ucn-III activates ERK1/2-p42 , 44 in Chinese hamster ovary cells stably expressing CRFR1 ... Use of the G ( i ) and G ( o ) protein inhibitor pertussis toxin showed that ERK1/2-p42 , 44 activation by Ucn-I via CRFR1 and CRFR2beta are both G ( i ) and/or G ( o ) protein dependent