Gene interactions and pathways from curated databases and text-mining

◀ Back to CAPN8

ABCA1 — CAPN8

Text-mined interactions from Literome

Wang et al., J Clin Invest 2003 (Arteriosclerosis) : In an apparent positive feedback loop, apoA-I binds ABCA1 , promotes lipid efflux, inhibits calpain degradation, and leads to increased levels of ABCA1
Hastie et al., J Biol Chem 2008 (Neoplasm Invasiveness...) : The findings suggest annexin 2 externalization is coupled to lipid efflux in prostate epithelium and that IFNgamma induces down-regulation of the protease binding anx2 ( t ) scaffold at the cell surface and consequently acts to suppress invasiveness through calpain mediated degradation of the lipid transporter ABCA1
Arakawa et al., J Lipid Res 2009 (Atherosclerosis) : Expression of ABCA1 is regulated by transcription of the gene and calpain mediated proteolytic degradation, and inhibition ABCA1 degradation results in increased ABCA1 and HDL biogenesis in vitro