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CD4 — CXCR5

Text-mined interactions from Literome

Mognetti et al., Clin Exp Immunol 2000 (Acquired Immunodeficiency Syndrome) : CD4 expression was detected in five of the 10 placentas, while membrane protein expression of CCR3, CXCR4 and CCR5 was detected in every case, despite quantitative differences among individuals
Li et al., Retrovirology 2013 : Increased CXCR5 and PD-1 expression was blocked by soluble CD4 or specific inhibitors of the Akt kinase, showing a direct relationship between CD4 signaling, T cell activation and Fas dependent cell death ... The same inhibitor, antibodies blocking the CD4 binding site on gp120, or soluble CD4 also prevented the increase in expression of CXCR5 or PD-1, and reduced the levels of Fas dependent cell death