Kawane et al., Biochem Biophys Res Commun 2001
:
The minimal PTH-suppressive region (PTHSR) was between +1 and +25 in exon U1, but the 5'-flanking region or Sp1 and MAZ binding sites also were required for PTH mediated repression
Hinton et al., Endocrinology 1991
:
The results suggested that the insulin mediated increase in PTH and SP-I secretion is largely due to its regulation of PTH and SP-I biosynthesis
Arps et al., Bone Miner 1987
:
The results support the concept that SP-I is responsible for stabilization of PTH within the secretory granules
Oka et al., Urol Int 1994
(Adenoma...) :
This suggests that normal cells in the neoplastic parathyroid glands may have their release of PTH rather than its synthesis suppressed, and also might support the hypothesis of some authors that chromogranin A or SP-I might contribute to stabilization of PTH or the secretory vesicle