Gene interactions and pathways from curated databases and text-mining

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CCL2 — CXCL10

Text-mined interactions from Literome

Shen et al., Zhonghua Yi Xue Za Zhi 2003 (Enterovirus Infections) : The expression of MIP-2 and IP-10 was induced post-infection, while SDF-1, MCP-1 , MCP-2, MCP-3, MCP-5, MDC, FKN and Ltn were constitutively expressed in myocardial tissue
Gómez et al., J Immunol 2005 (Nasal Polyps) : Epithelial IL-6 and soluble IL-6Ralpha were shown to participate in trans signaling, interacting with membrane associated gp130 to activate CCL-2 expression and inhibit additional CXCL8 production
Chizzolini et al., Arthritis Res Ther 2006 (Inflammation...) : Thus, Th1 and Th2 cells preferentially induced production of IFN-gamma inducible protein ( IP ) -10 and IL-8, respectively, whereas monocyte chemoattractant protein (MCP)-1 was equally induced by both subsets at mRNA and protein levels
Cheng et al., J Clin Invest 2007 (Atherosclerosis...) : One week of shear stress alterations induced expression of IFN-gamma-inducible protein-10 ( IP-10 ) exclusively in the LSS region, whereas monocyte chemoattractant protein-1 ( MCP-1 ) and the mouse homolog of growth regulated oncogene alpha ( GRO-alpha ) were equally upregulated in both LSS and OSS regions
Laine et al., Biochem Biophys Res Commun 2007 : Palmitic acid ( PA ), the predominant saturated FFA released from adipose tissue, but not unsaturated FFA, induced an approximately 6-fold ( p < 0.05 ) increase in IP-10 gene expression ( and 2- to 4-fold increases in IL-8, MCP-1 , COX-2, and MIG )
McKimmie et al., Biochem Biophys Res Commun 2010 : Bacterial associated molecules induced the preferential expression of CCL2 , CXCL1, CCL20 and CCL3 whilst a virus associated dsRNA analogue preferentially up-regulated CXCL10 and CCL5
Li et al., J Clin Endocrinol Metab 2011 (Inflammation...) : In IL-1ß- or TNF-a stimulated first trimester decidual cells, NF?B inhibitor suppressed production of all six chemokines ; JUN NH2-terminal kinase inhibitor inhibited secretion of CCL2 , CCL4, and CCL5 ; and MAPK kinase and p38 inhibitor decreased production of CXCL8
Lai et al., Int J Gynecol Cancer 2011 (Genital Neoplasms, Female...) : Similar treatment in HeLa cells caused increases in the mRNA levels of CCL2, CXCL2 , IL-6, and IL-8, and in SKOV3 cells, mRNA levels of CCL2 , CCL20, CXCL1, CXCL2, IL-6, and IL-8 increased
Bussfeld et al., Cell Immunol 1998 : In comparison with fully infectious influenza A, 56 degrees C-inactivated virus induced a strong production of MCP-1 , MIP-1 alpha, and IP-10, while the release of MIP-1 alpha and IP-10 was substantially lower after exposure to UV-inactivated virus