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IRAK4 — MAPK1
Text-mined interactions from Literome
Didierlaurent et al., Mol Cell Biol 2006
:
Activation of interleukin-1
(IL-1) receptor ( IL-1R ), Toll-like receptor 2 (TLR2), and TLR4
triggers NF-kappaB and
mitogen activated protein kinase ( MAPK ) -dependent signaling, thereby initiating immune responses
Conner et al., J Exp Med 2009
:
In the MOLF/Ei TLR signaling network,
IRAK-2 promotes early nuclear factor kappaB (NF-kappaB) activity and is
essential for the activation of p38
MAPK
Oliveira et al., Infect Immun 2011
(Brucellosis...) :
To investigate the
role of
IRAK-4 in
mitogen activated protein kinase ( MAPK ) and NF-?B signaling pathways, macrophages were stimulated with B. abortus, and the signaling components were analyzed by protein phosphorylation
Dauphinee et al., Am J Physiol Heart Circ Physiol 2011
:
We find that Ga ( i/o ) -mediated activation of the
MAPK is
independent of the canonical MyD88,
interleukin-1 receptor associated kinase , and tumor necrosis factor receptor associated factor 6 signaling cascade in LPS stimulated cells