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EGF — NUP43

Text-mined interactions from Literome

Douziech et al., Cell Signal 1999 (Pancreatic Neoplasms) : In PANC-1 cells, EGF and bombesin stimulated p42 in gel activation ; p44 remained highly activated and unresponsive to stimuli and p38 did not respond
Cole et al., Endocrinology 1999 : Epidermal growth factor (EGF) also activated p42 and p44MAPK in a time- ( peak at 5 min, return to basal within 2 h ) and dose dependent ( EC50 approximately 3 ng/ml ) fashion
Fabregat et al., Hepatology 2000 : We show here that EGF activates p42 and p44 mitogen activated protein kinases ( MAPK )
van Rossum et al., J Biol Chem 2001 (MAP Kinase Signaling System) : p42/44(MAPK) in response to epidermal growth factor was not only phosphorylated via the Raf-MEK pathway but mainly through protein kinase C ( PKC ) or a related or unrelated kinase in which the phosphorylated p42/44(MAPK) corresponded with cPLA(2) activity
Martin et al., J Biol Chem 2003 (MAP Kinase Signaling System) : Collectively, these findings indicate that IGFBP-3 enhances EGF signaling and proliferative effects in breast epithelial cells via increased EGF receptor phosphorylation and activation of p44/42 and p38 MAP kinase signaling pathways
Horikawa et al., Invest Ophthalmol Vis Sci 2003 : To compare activation of the p42/p44 mitogen activated protein kinase ( MAPK ) by cholinergic agonists and epidermal growth factor (EGF) in cultured human and rat goblet cells
Gui et al., J Biol Chem 2003 (MAP Kinase Signaling System) : In response to treatment with EGF, the EGF receptor was phosphorylated, which was correlated with phosphorylation and activation of p42/44 mitogen activated protein kinases
Raspaglio et al., Oncol Res 2003 (Carcinoma, Squamous Cell...) : Mitogen activated protein kinase ( MAPK ) analysis revealed that in Hep2 cells, but not in CO-K3 cells, EGF induced a time dependent phosphorylation of p42 , p44, p38, and p46
Arnoletti et al., J Gastrointest Surg 2004 (Adenocarcinoma...) : Likewise, EGF dependent phosphorylation of MAPK p44/42 was blocked by Erbitux treatment in MIA PaCa-2 but not BxPC-3 cells
Sedehizade et al., Neurochem Res 2005 : There, we studied the influence of thrombin, which raises Ins ( 1,3,4,5 ) P4, on membrane translocation of GFP-p42 ( IP4 ), induced by epidermal growth factor (EGF)
Heo et al., Cell Physiol Biochem 2006 : EGF also increased phosphorylation of p38 MAPK and p44/42 MAPKs, which was blocked by genistein or bisindolylmaleimide I, respectively
Liu et al., Proc Natl Acad Sci U S A 2006 : EGF strongly stimulates p42 to bind ErbB3, and the association depends on PKC mediated phosphorylation of Ebp1
Capó-Aponte et al., Cell cycle (Georgetown, Tex.) 2007 : The KCC inhibitor [ ( dihydroindenyl ) oxy ] alkanoic acid ( DIOA ) and KCC activator N-ethylmaleimide ( NEM ), suppressed and enhanced EGF induced p44/42MAPK activation , respectively
Harwood et al., J Biol Chem 2008 (MAP Kinase Signaling System) : Higher concentrations of rapamycin ( > or =100 ng/ml ) were required to inhibit epidermal growth factor (EGF) induced phosphorylation of p44/42 ( Thr ( 202 ) )
Park et al., Cell Prolif 2008 (Calcium Signaling) : EGF induced phosphorylation of p38 and p44/42 MAPKs, and this was blocked by SB 203580 ( a p38 MAPK inhibitor ) and PD 98059 ( a p44/42 MAPK inhibitor ), respectively
Suh et al., J Cell Physiol 2009 : Interleukin-6 promotes 2-deoxyglucose uptake through p44/42 MAPKs activation via Ca2+/PKC and EGF receptor in primary cultured chicken hepatocytes
Jeon et al., Lung Cancer 2010 (Carcinoma, Non-Small-Cell Lung) : In cholesterol depleted cells, EGF induced phosphorylation of Src, Akt, and p44/42 in the detergent-insoluble fraction were inhibited whereas phosphorylation of GSK-3beta was unaffected
Kimura et al., Biol Pharm Bull 2011 : In addition, the growth-inhibitory effects of dexamethasone did not affect EGF induced p42 mitogen activated protein ( MAP ) kinase phosphorylation
Nakashima et al., Molecular cancer 2011 (Carcinoma...) : In addition, EGF induced phosphorylation of p44/p42 mitogen activated protein kinase and Akt were also enhanced by Y27632 or ROCK-siRNA
Traverse et al., Curr Biol 1994 : In contrast, stimulation with epidermal growth factor induces a transient activation of p42 and p44 MAP kinases without pronounced nuclear translocation and does not trigger cell differentiation
Lamy et al., J Biol Chem 1993 : ( i ) As in other systems, EGF and phorbol esters induced p42 and p44 MAP kinases phosphorylation on tyrosine, serine, and threonine
Chajry et al., Eur J Biochem 1996 : Regulation of p42 mitogen-activated-protein kinase activity by protein phosphatase 2A under conditions of growth inhibition by epidermal growth factor in A431 cells
Cybulsky et al., Biochem Biophys Res Commun 1997 : In addition, EGF stimulated the activity and tyrosine phosphorylation of p42 mitogen activated protein ( MAP ) kinase ( ERK2 ) in collagen-adherent GEC, but not in cells on plastic
MacKenzie et al., Biochem J 1997 : Previous studies have shown that the activation of p44 and p42 mitogen activated protein ( MAP ) kinases ( ERK1 and ERK2 ) by growth hormone (GH) and phorbol esters, but not by epidermal growth factor , in 3T3-F442A preadipocytes is dependent on protein kinase C ( PKC )
Tiganis et al., Mol Cell Biol 1998 : We examined the effects of TC45 on EGFR signaling and observed that it did not modulate EGF induced activation of p42Erk2
Putz et al., Cancer Res 1999 (Prostatic Neoplasms) : The effects of EGF on p42/ERK2 are potentiated by forskolin in both cell lines
Aplin et al., J Cell Sci 1999 : These data indicate that a limited degree of adhesion mediated cytoskeletal organization and focal adhesion complex formation are required for efficient EGF activation of p42 and p44-MAPKs