Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
PTK2
→
Complex of GDNF-NCAM1
(increases, GDNF/NCAM1 Activity)
Evidence: Carlos Ibanez and collaborators demonstrated that neural cell adhesion molecule (NCAM) functions as an alternative signaling receptor for GFLs (fig. 2). In the presence of GFR-a, GDNF binds with high affinity to p140-NCAM and intracellularly activates the Src-like kinase c-Fyn and the focal adhesion kinase FAK [29].