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IFNB1 — OAS1

Text-mined interactions from Literome

Massa et al., J Neurovirol 1999 : Analysis of OAS gene promoter activity indicated that induction of the OAS gene by IFN-beta was dependent on a region containing the interferon stimulated responsive element ( ISRE ) ... While the OAS and MHC Class I site bound equal amounts of the transcriptional repressor IRF-2, the OAS-ISRE preferentially interacted with the transcriptional activator ISGF3 in response to IFN-beta
Satoh et al., J Interferon Cytokine Res 1999 (Asthma) : Additionally we found 2',5'-oligoadenylate synthetase ( 2',5'-OAS ) induction by low-dose oral administration ( LDOA ) of IFN-beta to the same extent as by subcutaneous administration in whole blood in vivo
Matsumura et al., Journal of drug targeting 2002 (Hepatitis B...) : Percutaneous insonation in mouse liver following IFN-beta injection with the ultrasound power level used at clinical diagnosis enhanced the IFN-beta induced increase of 2',5'-oligoadenylate synthetase ( 2-5AS ) levels in the liver
Takane et al., Jpn J Pharmacol 2002 : IFN-beta induced 2',5'-OAS activity was more potent after the drug injection during the late dark phase
Almeida et al., Antiviral Res 2008 (Bunyaviridae Infections) : IFN alpha2, IFN beta , IL-29 and IL-28a induced the expression of 2',5'-oligoadenylate synthetase ( 2'5'OAS ) and 6-16 genes
Pulit-Penaloza et al., Virology 2012 : Also, IFN beta induction of Oas1a was STAT1- and STAT2 dependent, while induction of Oas1b was STAT1 independent but STAT2 dependent
Yan et al., Proc Natl Acad Sci U S A 1989 : Bovine serum also did not affect 2',5'-OAS mRNA induction by IFN-alpha/beta ... The poly ( ADP ) -ribose synthetase inhibitor 3-aminobenzamide suppressed IFN-alpha/beta induced 2',5'-OAS gene expression ... These results suggest that in quiescent BALB/c 3T3 cells ( i ) the 2',5'-OAS gene is not responsive to the three major signal transduction pathways activated by diacylglycerol, Ca2+, and cAMP ; ( ii ) induction of the 2',5'-OAS gene by IFN-alpha/beta is decreased by activation of the protein kinase C pathway but enhanced by elevation of intracellular [Ca2+ ]
Ruzicka et al., Cancer Res 1987 (Carcinoma...) : Induction of 2',5'-oligoadenylate synthetase in ACHN cells and antiproliferative activity in RT112, RT4, T24 ( human transitional cell carcinoma ), and ACHN cells by IFN-beta ser decreased significantly 48 h following plating
Knight et al., Proc Natl Acad Sci U S A 1985 (Burkitt Lymphoma) : We have also detected induction of the ( 2'-5 ' ) oligoadenylate synthetase ( 2-5A synthetase ) gene in IFN-beta treated Daudi cells
Ralph et al., J Immunol 1995 (Melanoma) : Pretreatment of the three melanoma cell lines with the tyrosine kinase inhibitors, Herbimycin A or Genistein, produced a dose dependent inhibition of the antiviral action of IFN-alpha, -beta, and -gamma and the induction of OAS by IFN-beta