Gene interactions and pathways from curated databases and text-mining

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IL4 — LCK

Text-mined interactions from Literome

Tamura et al., J Immunol 1995 : The anti-CD3 stimulation did not cause Lck activation in either the Th1 or Th2 clone, although remarkable activation was induced in both clones following anti-CD4 stimulation, indicating that Lck activation was not required for either IL-2 or IL-4 production of Th cells
Musso et al., J Exp Med 1994 : IL-4 and IL-13 induce Lsk , a Csk-like tyrosine kinase, in human monocytes ... In fact, IFN-gamma, but not IL-2, efficiently blocked Lsk induction by IL-4 or IL-13