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CD4 — IL23A

Text-mined interactions from Literome

Langrish et al., J Exp Med 2005 (Encephalomyelitis, Autoimmune, Experimental...) : Using passive transfer studies, we confirm that these IL-23 dependent CD4 ( + ) T cells are highly pathogenic and essential for the establishment of organ-specific inflammation associated with central nervous system autoimmunity
Vanden Eijnden et al., Eur J Immunol 2005 : We investigated the effect of recombinant human ( rh ) IL-23 on cord blood CD4+ and CD8+ T cells during polyclonal activation
Cho et al., J Immunol 2006 (Arthritis...) : We investigated the pathogenic role of IL-23 in CD4 ( + ) T cells in mice lacking the IL-1R antagonist ( IL-1Ra ( -/- ) ), an animal model of spontaneous arthritis
Matsui et al., Hepatology research : the official journal of the Japan Society of Hepatology 2007 : IL-12 leads to the development ofinterferon-gamma producing T-helper type 1 ( Th1 ) cells, whereas IL-23 amplifies and stabilizes a new CD4 ( + ) T-cell subset, Th17 producing IL-17
Lyakh et al., Immunol Rev 2008 : IL-23 , IL-6, transforming growth factor ( TGF-beta1 ), and IL-1beta in supernatants from activated human DCs induce human naive CD4 ( + ) T cells to produce IL-17
Reay et al., Cancer Gene Ther 2009 (Fibrosarcoma) : In addition, we have shown that the antitumor activity of IL-23 is independent of IL-17, perforin and Fas ligand, but dependent on interferon-gamma, CD4 ( + ) and CD8 ( + ) T cells
Jang et al., J Leukoc Biol 2009 : Furthermore, production of IL-23 in CBDC costimulated with LPS and IL-12 caused CD4 ( + ) CD45RO ( + ) memory cells to increase IFN-gamma production
Nagasaka et al., Biochem Biophys Res Commun 2009 : These results suggest that SF-DCs tend to produce IL-23 and can consequently induce the IL-17 producing CD4 ( + ) T cells
Kondo et al., Immunology 2009 (Myositis) : Taken together, these results suggest that proinflammatory cytokines enhance Fas mediated apoptosis of muscle cells, and that the Fas/FasL interaction between invading dendritic cells and CD4 ( + ) T cells induces local production of IL-23 and proinflammatory cytokines, which can promote the proliferation of Th17 cells and enhance Fas mediated apoptosis of muscle cells, respectively
Liu et al., J Leukoc Biol 2011 (Colitis, Ulcerative...) : Importantly, IL-23 promoted IBD PB- or LP-CD4 ( + ) T cells to differentiate into Th17 cells, characterized by increased expression of IL-17A and RORC
Maddur et al., J Clin Immunol 2013 : Naive CD4 ( + ) T cells were stimulated in the presence of TGF-ß, IL-21, and IL-23 for the differentiation of Th17 cells
Cargnelutti et al., Immunol Cell Biol 2013 : In addition, we found that CD4 ( + ) T cells from TNFRp55 ( -/- ) mice controlled antigen-specific IL-12/23 ( p40 ) production in recipient WT mice