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DUSP2 — EPHB2
Text-mined interactions from Literome
Kar-Roy et al., J Biol Chem 2004
:
This is the first example of a viral protein regulating
ERK activation by inhibition of its cognate
dual specificity phosphatase
Hu et al., Mol Cell Biol 2006
(Lung Neoplasms) :
While activated ERK phosphorylates Hsf4b,
DUSP26 controls the activity of
ERK , leading to phosphorylation/dephosphorylation of Hsf4b, altering its ability to bind DNA
Caunt et al., J Biol Chem 2008
(MAP Kinase Signaling System) :
Overexpression of DUSP1, -2, or -4 prevented
ERK2 activation, but only
DUSP2 and -4
caused ERK2-GFP nuclear accumulation or could be immunoprecipitated with ERK2
Maloney et al., Am J Physiol 1999
:
ANG II-induced activations of Fyn, Raf-1, and
ERK were augmented in cells pretreated with BAPTA-AM, but ANG II-induced expression of the
dual-specificity phosphatase mitogen activated protein kinase phosphatase-1 was
blocked by BAPTA-AM pretreatment