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DLX4 — SLC22A3

Text-mined interactions from Literome

Sun et al., Reprod Sci 2011 (Pre-Eclampsia) : To elucidate the role of DLX4 in trophoblast EMT and preeclampsia, we investigated the expression of DLX4 in preeclampsia affected placentas and the effect of DLX4 on EMT in trophoblast derived JEG-3 cells
Zhang et al., International journal of biological sciences 2012 (Breast Neoplasms...) : Taken together, these data from both cell models and tumor tissues demonstrate that DLX4 not only upregulates TWIST expression but also induces EMT and tumor metastasis ... Altogether, we propose a new pathway in which DLX4 drives expression of TWIST to promote EMT , cancer migration, invasion and metastasis