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DHFR — E2F7

Text-mined interactions from Literome

Fry et al., J Biol Chem 1999 : Previously, we have demonstrated that cell cycle regulation of murine dihydrofolate reductase (dhfr) expression requires E2F mediated activation of the dhfr promoter in S phase
Sahin et al., International journal of biological sciences 2010 : For example, E2F-1 acts as part of the repression complex with pRB in the expression of DHFR , b-myb, TK and cdc2 in asynchronously growing cells ; on the other hand, E2F-1 acts as an activator in the expression of the same genes in cells that are re-entering the cycle
Blake et al., Mol Cell Biol 1989 : Thus, the interaction of E2F with the DHFR promoter is required for efficient expression of the DHFR gene
Margolis et al., J Virol 1995 : Interaction of the 72-kilodalton human cytomegalovirus IE1 gene product with E2F1 coincides with E2F dependent activation of dihydrofolate reductase transcription
Slansky et al., Mol Cell Biol 1993 : In this study, we focused on the role of E2F in the growth regulation of DHFR