Gene interactions and pathways from curated databases and text-mining

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BAX — EGF

Text-mined interactions from Literome

Ge et al., Biol Reprod 2009 : On the other hand, inhibition of EGFR, Ca ( 2+ ) /PKC, or NFKB1 abolished the EGF stimulated increase in the expression of cyclins CCND1 and CCNE1, cyclin dependent kinase 6 (CDK6), CDK2, and BCL2, and restored the EGF induced inhibition of BAX expression and caspase 3/9 activity, indicating that EGFR, PKC, and NFKB1 signaling cascades were involved in EGF stimulated DNA synthesis and antiapoptosis action
Iwayama et al., Mol Cell Biochem 2013 : Effect of ceramide on expression of mitochondrial Bax and phosphorylated ( p ) -ERK, p38MAPK and JNK, that of MAPKs inhibition, and of EGF in the presence or absence of MAPKs inhibition on ceramide induced apoptosis were examined in HK-2 cells