UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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BCAR1 — HGF

Pathways - manually collected, often from reviews:

NCI Pathway Database Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met): Crk/p130 Cas complex (BCAR1-CRK) → HGF(dimer)/MET(dimer) complex (MET-HGF) (modification, collaborate)
Garcia-Guzman et al., Oncogene 1999 *, Riordan et al., Biochem J 2000 *, Lamorte et al., Oncogene 2000
Evidence: physical interaction
NCI Pathway Database Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met): HGF(dimer)/MET(dimer) complex (MET-HGF) → p130 Cas (BCAR1) (modification, activates) Garcia-Guzman et al., Oncogene 1999 *, Riordan et al., Biochem J 2000 *, Lamorte et al., Oncogene 2000
Evidence: physical interaction