Gene interactions and pathways from curated databases and text-mining

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ABCC1 — JUN

Text-mined interactions from Literome

Chai et al., Hepatology 2012 (Cholestasis...) : In HepG2 cells, TNFa treatment induced SP1 and MRP3/ABCC3 expression in a dose- and time dependent manner, where increased phosphorylation of c-Jun NH2-terminal kinase/stress activated protein kinase ( JNK/SAPK ) was also detected
Fang et al., Anat Rec (Hoboken) 2012 (Carcinoma, Hepatocellular...) : Our results demonstrated that mda-7/IL-24 could restore the drug sensitivity through the downregulation of MDR1, MRP1 , and LRP expression, as well as the transcriptional activation of AP-1 and NF-?B and effectively reverse MDR