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Text-mined interactions from Literome
Chai et al., Hepatology 2012
(Cholestasis...) :
In HepG2 cells, TNFa treatment
induced SP1 and
MRP3/ABCC3 expression in a dose- and time dependent manner, where increased phosphorylation of
c-Jun NH2-terminal kinase/stress activated protein kinase ( JNK/SAPK ) was also detected
Fang et al., Anat Rec (Hoboken) 2012
(Carcinoma, Hepatocellular...) :
Our results demonstrated that mda-7/IL-24 could restore the drug sensitivity through the downregulation of MDR1,
MRP1 , and LRP expression, as well as the transcriptional
activation of
AP-1 and NF-?B and effectively reverse MDR