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EPHB2 — EPO

Text-mined interactions from Literome

Nosaka et al., J Biol Chem 1999 (MAP Kinase Signaling System) : Moreover, the Epo induced activation of ERK1 and ERK2 was augmented and prolonged in cells inducibly overexpressing CrkL ... Most importantly, a CrkL mutant defective in the SH2 or N-terminal SH3 domain showed an inhibitory effect on the Epo induced activation of ERK2
Meloni et al., J Neurosci Res 2006 (Ischemia) : In this study we confirmed the presence of the erythropoietin (EPO) receptor on both cultured cortical neurons and PC12 cells and showed that EPO can induce changes in p38, ERK , and JNK signaling molecules in these cells
Chan et al., Life Sci 2007 (Myocardial Reperfusion Injury) : EPO increased Jak2 and ERK activity, decreased MMP expression, increased TIMP-4 expression, and prevented collagen degradation in IR hearts
Mirmohammadsadegh et al., J Invest Dermatol 2010 (Anemia...) : When assessing the functionality of the EpoR signaling pathway, recombinant human Epo led to the phosphorylation of JAK-2, signal transducers and activators of transcription 3 ( STAT3 ), and ERK1/2 in several of the melanoma cell lines that were analyzed
Frisan et al., Haematologica 2010 (Myelodysplastic Syndromes) : Erythropoietin dependent proliferation and survival, and phospho ( p ) -ERK1/2 expression in steady state and after erythropoietin stimulation were defective in cultured erythroblasts
Kumar et al., Oncogene 2012 (Disease Progression...) : EpoR knockdown in melanoma cells resulted in diminished ERK phosphorylation in response to Epo stimulation, decreased cell proliferation and increased response to the inhibitory effect of hypoxia and cisplatin in vitro
Talbot et al., PloS one 2011 (MAP Kinase Signaling System...) : Aconitase regulation of erythropoiesis correlates with a novel licensing function in erythropoietin induced ERK signaling
Hu et al., Kidney Int 2013 : Here we found in rat kidney and in a rat renal tubular epithelial cell line ( NRK cells ) EpoR transcript and antigen, and EpoR activity signified as EPo induced phosphorylation of Jak2, ErK , Akt, and Stat5 indicating the presence of functional EpoR
Okuda et al., Int J Oncol 2013 : EPO induced a rapid activation of ERK and also phosphorylation of endogenous Raf
Todokoro et al., Biochem Biophys Res Commun 1994 : We show here that binding of erythropoietin to its receptor induced activation of protein tyrosine kinases including Jak2, and of Ras, Raf-1, mitogen activated protein ( MAP ) kinase kinase and MAP kinases ( ERK1 and ERK2 )
Sui et al., Blood 1998 : Synergistic activation of MAP kinase (ERK1/2) by erythropoietin and stem cell factor is essential for expanded erythropoiesis
Nagata et al., Blood 1998 (Leukemia, Erythroblastic, Acute) : We found that all MAP kinases examined, ERK1, ERK2 , p38, JNK1, and JNK2, were rapidly and transiently activated by erythropoietin (Epo) stimulation in SKT6 cells, which can be induced to differentiate into hemoglobinized cells in response to Epo