Gene interactions and pathways from curated databases and text-mining

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CDH1 — LPA

Text-mined interactions from Literome

Qian et al., EMBO J 2004 : E-cadherin did not regulate a constitutively active mutant RTK ( Neu* ) or the ligand dependent activation of LPA receptors or muscarinic receptors, which are two classes of G protein coupled receptors
Carothers et al., Exp Cell Res 2006 : We treated Apc+/+ ( WT ) littermate small intestine with EGTA, an inhibitor of E-cadherin , and with LPA , an RhoA activator ; both induced effects on adhesion and kinase activity that mimicked the Min/+ phenotype
Gil et al., Gynecol Oncol 2008 (Neoplasm Invasiveness...) : To evaluate the role of LPA in regulating E-cadherin cell surface expression, adhesion, and invasion in epithelial ovarian carcinoma ( EOC ) cells
He et al., J Biol Chem 2009 (Lung Injury) : This study provides evidence that LPA enhances pulmonary epithelial barrier integrity through protein kinase C (PKC) delta- and zeta mediated E-cadherin accumulation at cell-cell junctions
Liu et al., Journal of oncology 2012 : LPA induced loss of E-cadherin was concentration and time dependent ... LPA increased MMP-9 expression and promoted MMP-9 catalyzed E-cadherin ectodomain shedding