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CASP1 — SERP2
Text-mined interactions from Literome
MacNeill et al., Virology 2006
(Myxomatosis, Infectious) :
SERP2-D294E prevented inhibition of
caspase-8 , caspase-10 and granzyme-B ; and MYX-SERP2-D294E failed to block apoptosis in RK-13 cells, but was fully virulent in rabbits
Viswanathan et al., PloS one 2012
(Carotid Stenosis...) :
With analysis in vitro of human cells in culture,
Serp-2 selectively
inhibited T cell
caspase activity and blocked cytotoxic T cell ( CTL ) mediated killing of T lymphocytes ( termed fratricide )
Petit et al., J Virol 1996
:
The biological relevance of this new serpin from MV was monitored, and it was shown that
Serp2 could
inhibit human
interleukin-1 beta converting enzyme activity
Messud-Petit et al., J Virol 1998
(Myxomatosis, Infectious) :
Serp2 , an
inhibitor of the
interleukin-1beta converting enzyme , is critical in the pathobiology of myxoma virus