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EGFR — GAST

Text-mined interactions from Literome

Sinclair et al., Am J Physiol Gastrointest Liver Physiol 2004 : Gastrin regulates the heparin binding epidermal-like growth factor promoter via a PKC/EGFR dependent mechanism
Konturek et al., Gut 1997 (Duodenal Ulcer...) : ( 1 ) H pylori infection in patients with duodenal ulcer was accompanied by enhanced plasma gastrin and increased mucosal content and expression of TGF alpha, EGF, and EGFr ; ( 2 ) H pylori eradication resulted in ulcer healing, reduction in plasma gastrin , and enhancement of gastric ( but not salivary ) luminal release of EGF, particularly after pentagastrin stimulation ; and ( 3 ) enhanced mucosal content and expression of TGF alpha, EGF, and EGFr and increased luminal release of EGF may contribute to ulcer healing after eradication of H pylori