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CDKN1A — FLI1

Text-mined interactions from Literome

Gascoyne et al., Oncogene 2004 : Furthermore, overexpression of EWS/Fli-1 but not EWS or Fli-1 inhibits Brn-3a associated growth arrest and neurite outgrowth in neuronal cells, and specifically inhibits Brn-3a dependent activation of p21 and SNAP-25 transcription
Sakimura et al., Int J Cancer 2005 (Neuroectodermal Tumors, Primitive...) : We have previously reported that p21 ( Waf1/Cip1 ) expression was inhibited by EWS-Fli1 in EFTs
Nakamura et al., Int J Oncol 2007 (Sarcoma, Ewing) : We have reported that EWS-Fli1 inhibits p21 ( waf1/cip1 ) and p27 ( kip1 ) expressions, which are degraded by the ubiquitin-proteasome pathway
Ban et al., Cancer Res 2008 (Sarcoma, Ewing) : Studying 6 ESFT cell lines, silencing of EWS-FLI1 in a wild-type p53 context resulted in increased p53 and p21 ( WAF1/CIP1 ) levels, causing cell cycle arrest