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SULT2A1 — TLR2
Text-mined interactions from Literome
Feterowski et al., Int Immunol 2005
(Peritonitis) :
While pre-treatment with MALP-2 does not involve differential expression of TLR and IL-1R associated kinase proteins,
ST2 , a negative
regulator of
TLR signaling, was up-regulated after treatment of mice with either MALP-2 or N-alpha-palmitoyl-S- [ 2,3-bis ( palmitoyloxy ) - ( 2RS ) -propyl ] -L-cysteine
Liu et al., J Immunol 2010
:
However, it is undetermined whether
ST2 negatively
regulates TLR2 signaling and furthermore, whether a TLR2 agonist, bacterial lipoprotein (BLP) induced tolerance is dependent on ST2
Buckley et al., J Immunol 2011
(Bacterial Infections...) :
ST2 , a member of the Toll/IL-1R superfamily, negatively
regulates both
TLR2 and TLR4 signaling