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CD47 — IL12B
Text-mined interactions from Literome
Armant et al., J Exp Med 1999
:
We report here that engagement of
CD47 by either monoclonal antibody, its natural ligand thrombospondin ( TSP ), or 4N1K ( a peptide of the COOH-terminal domain of TSP selectively binding CD47 )
inhibits IL-12 release by monocytes
Bouguermouh et al., J Immunol 2008
(Dermatitis, Contact) :
Although selective
CD47 deficiency on DCs
led to increased
IL-12p70 production, CD47 ( -/- ) Tg T cells produced more IFN-gamma and displayed higher T-bet expression than CD47 ( +/+ ) Tg T cells in response to OVA loaded CD47 ( -/- ) DCs