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IGFBP3 — IRF6

Text-mined interactions from Literome

Priego et al., Am J Physiol Endocrinol Metab 2004 : NO plays a role in LPS induced decreases in circulating IGF-I and IGFBP-3 and their gene expression in the liver ... In this study, we administered aminoguanidine, a relatively selective inducible nitric oxide synthase (iNOS) inhibitor, to study the role of nitric oxide ( NO ) in LPS induced decrease in IGF-I and IGFBP-3 ... Aminoguanidine administration blocked the inhibitory effect of LPS on both IGFBP-3 serum levels and its hepatic mRNA levels
Priego et al., J Endocrinol 2005 (Bacterial Infections) : Dexamethasone pretreatment attenuated the LPS induced decrease in IGFBP-3 gene expression in the liver and prevented the LPS induced decrease in IGFBP-3 gene expression in the kidney
Granado et al., J Endocrinol 2006 (Body Weight...) : Pretreatment of the animals with gadolinium chloride blocked the inhibitory effect of LPS on body weight, and on serum concentrations of IGF-I, IGFBP-3 and nitrites, as well as growth hormone receptor (GHR), IGF-I and IGFBP-3 gene expression in the liver ... These results suggest that Kupffer cells are important mediators in the inhibitory effect of LPS on GHR, IGF-I and IGFBP-3 gene expression in the liver, leading to a decrease in serum concentrations of IGF-I and IGFBP-3
Thomsen et al., In Vivo 2008 (Insulin Resistance...) : LPS reduced IGF-I and IGFBP-3 by 20 % in the cirrhosis group