Gene interactions and pathways from curated databases and text-mining

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IFNG — IKBKG

Text-mined interactions from Literome

Chae et al., Immunopharmacol Immunotoxicol 2004 : TNF-alpha plus IFN-gamma can induce extracellular signal regulated kinase ( ERK ), IKK , IkappaB degradation and NF-kappaB activation
Kårehed et al., Mol Immunol 2007 : We further show that IFN-gamma induction of FcgammaRI upregulation is dependent on the NFkappaB pathway, as evidenced by inhibition of NFkappaB using a phosphorylation defective IkappaBalpha ( S32A/S36A ) mutant, or inhibiting the IkappaB-kinase (IKK) by treatment with BMS345541
Hong et al., J Surg Res 2010 : Immunocomplex assay involving GST-IKK revealed that cAMP inhibited IL-1beta plus IFNgamma induced IKK activity