Gene interactions and pathways from curated databases and text-mining

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IFNG — LYZ

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: LYZ → IFNG (increases, IFNG Translocation)
    Evidence: Treatment of nMNC with cisplatin, LPS, MDP or rIFN-gamma resulted in enhanced release of lysozyme into the culture medium as compared to untreated nMNC

Text-mined interactions from Literome

Walter et al., Br J Haematol 2000 (Leukemia, Monocytic, Acute...) : SigM5 constitutively secreted interleukin (IL)-2, IL-8, IL-10, tumour necrosis factor (TNF)-alpha, ferritin, lysozyme , N-elastase and neopterin upon stimulation with interferon (IFN)-gamma
Lewis et al., Immunology 1990 : Differential effects of LPS, IFN-gamma and TNF alpha on the secretion of lysozyme by individual human mononuclear phagocytes : relationship to cell maturity
Mikkelsen et al., Fish Shellfish Immunol 2013 (Fish Diseases...) : While, no measureable activations of interferon gamma ( IFN? ) , IL-8, cathelicidin, LBP/BPI and G-type lysozyme were found